Who should consider fertility medications?
- Women who do not have regular menstrual cycles (such as women with PCOS or amenorrhea)
- Couples diagnosed with unexplained infertility.
- Couples with mild male factor or those utilizing donor sperm, who have been unsuccessful with IUI alone (below).
What medications may be used?
- There are two oral medications that are most commonly used: clomiphene (Clomid®) and letrozole (Femara®).
- Oral medications are taken at the beginning of the woman’s cycle, starting between day 3 and 5 of the cycle and continued for 5 days.
- A transvaginal ultrasound will be performed, usually around cycle days 10-12, to evaluate follicular response to the medication. Ideally, only one follicle will have responded to the medication. Some women may have two or more follicles, which could result in a multiple pregnancy.
- Your physician may prescribe an injectable medication called human chorionic gonadotropin (HCG) to be given at a specified time to induce ovulation, about 40 hours before the IUI. This medication will cause the egg to leave the follicle and start moving down the fallopian tube.
- For other patients, injectable medications may be prescribed to stimulate the ovaries. Gonadotropins such as Menopur®, Bravelle®, Gonal-F®, or Follistim® will be prescribed by your doctor and you will be closely monitored by ultrasound for follicle development. Some women develop multiple follicles with gonadotropin therapy and risks of this therapy include multiple pregnancy.
Intrauterine Insemination (IUI)
Who should consider IUI?
- Women using donor sperm to achieve a pregnancy
- Same sex female couples.
- Single females
- Couples in which the male partner has low sperm counts or azoospermia (no sperm).
- Women who have been diagnosed with unexplained infertility or infertility related to endometriosis.
- Couples with mild male factor infertility: semen analysis showing below-average sperm concentration, weak movement of sperm or abnormalities in sperm size and shape.
What is IUI?
- The IUI procedure is a basic reproductive technique that deposits washed sperm into the uterus at the time of ovulation. The sperm source can be fresh or frozen, from a male partner or a donor. The goal is for the sperm to swim into the fallopian tube and fertilize a waiting egg, resulting in a pregnancy.
- IUI can be coordinated with your normal cycle or with the fertility medications above.
Why chose NRM?
Located in Colchester, Vermont, we provide a convenient, confidential and comfortable setting with an experienced team of doctors and nurses dedicated to meeting your needs. Click to learn more about our Physicians and Patient Care Team.
When you are ready, the next step is to schedule a consultation where we can meet with you to develop a personalized fertility plan designed to deliver the family of your dreams.