Northeastern Reproductive Medicine

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NRM patients share their heartbreaking story– with a happy ending!

Posted February 16, 2018 by Claire

Don’t miss this amazing story about how a new technology can help couples conceive a healthy child

NRM is the only clinic in Vermont offering blastocyst biopsies for  pre-implantation genetic screening “PGD”, a state-of-the-art procedure utilized when undergoing IVF to select embryos free of a specific disease. This technology offers hope to individuals or couples carrying diseases that can be devastating or even fatal, and improve the likelihood of healthy pregnancy. PGD assists individuals or couples who are known carriers of a specific genetic disease, such as Cystic Fibrosis, Spinal Muscular Atrophy, or other single gene disorders, and allows identification of genetic disease to avoid passing the genetic disorder to offspring.

Watch the WCAX story here!

If you or your partner carry a known genetic disorder, the first step is to work with your physician and the genetics laboratory to set-up a probe that can detect the gene of concern. 

What is the process of PGD?

Following IVF with ICSI, the first step is embryo biopsy. We have highly experienced embryologists who can perform microsurgical removal of one cell from a 3-day old or a few cells from a 5or 6-day old embryo. The biopsied cells are then placed in special containers in dry ice, and sent to a central PGD laboratory where each sample is analyzed independently.

We prefer to obtain testing cells from the embryo through a blastocyst (day-5) biopsy, because at this stage the inner cell mass, which will develop into the fetus, has differentiated from the trophectoderm, which will later develop into the placenta and membranes. A biopsy at this stage involves the removal of a number of cells (3-10) from the trophectoderm. This type of biopsy is advantageous in that no cells are extracted from the inner cell mass, while still obtaining multiple cells for carrying out PGS, which leads to improved accuracy. Furthermore, blastocysts are more robust than earlier embryonic stages and tolerate biopsy exceptionally well. The blastocyst also is the best stage for vitrification (flash freezing, into a “glass-like” state) with almost 100% survival rate.

Learn more about PGD and the partner technology, PGS, or pre-implantation genetic screening, through this link. 

Filed Under: NRM News

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Fertility Preservation Services

NRM offers freezing and storage of eggs, sperm, or embryos for individuals with a recent cancer diagnosis who desire future fertility, or those who elect to delay childbearing for other reasons.

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Referring Providers: Did you Know?

We want to work with you toward a common shared goal: maximizing reproductive health and increasing patients’ potential for successful pregnancies. We offer a set of referral services designed to help your patients take the first steps of fertility treatment Learn More.

Northeastern Reproductive Medicine

105 West View Road Suite 302
Colchester, Vermont 05446
1 (802) 655-8888

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